IGCSE · Practice questions · Monohybrid crosses

Predict the offspring.

Six original Cambridge-style questions on genetic vocabulary, complete genetic diagrams, ratios and probabilities from Punnett squares and using a test cross to find an unknown genotype.

Original questions All questions on this page are original work, written in the Cambridge IGCSE style. They are not from past papers. They test the same concepts and skills the syllabus rewards.
A full genetic diagram

Five lines, every time.

01
Recall
[4 marks]

Define (a) genotype, (b) homozygous, (c) heterozygous and (d) recessive allele.

  • (a) The genetic make-up of an organism, in terms of the alleles present. ✓
  • (b) Having two identical alleles of a particular gene. ✓
  • (c) Having two different alleles of a particular gene. ✓
  • (d) An allele that is only expressed when there is no dominant allele of the gene present in the genotype. ✓
02
Analysis
[5 marks]

In tomato plants, red fruit (R) is dominant to yellow fruit (r). Two heterozygous plants are crossed. Draw a complete genetic diagram and state the expected ratio of the offspring phenotypes.

  • Parents: red Rr × red Rr. ✓
  • Gametes: R and r from each parent. ✓
  • Punnett square: RR, Rr, Rr, rr. ✓
  • Phenotypes: RR, Rr, Rr red; rr yellow. ✓
  • Ratio 3 red : 1 yellow. ✓
03
Calculation
[3 marks]

A heterozygous red-fruited tomato plant (Rr) is crossed with a yellow-fruited plant (rr). 120 seeds grow into plants. (a) State the expected phenotype ratio. (b) Calculate the expected number of yellow-fruited plants. (c) State the probability that one particular seed grows into a red-fruited plant.

  • (a) Gametes R or r × r only, giving Rr and rr: 1 red : 1 yellow. ✓
  • (b) 120 ÷ 2 = 60 yellow-fruited plants. ✓
  • (c) 1 in 2 (0.5, or 50%). ✓
04
Explain
[3 marks]

Explain why a plant that is homozygous for an allele is pure-breeding, but a heterozygous plant is not.

  • A homozygous plant (for example TT) can only make gametes carrying one type of allele (T). ✓
  • Bred with an identical homozygous plant, all offspring have the same genotype and phenotype as the parents, so it is pure-breeding. ✓
  • A heterozygous plant (Tt) makes gametes carrying T or t, so its offspring can have different genotypes and show either phenotype: it is not pure-breeding. ✓
05
Explain
[4 marks]

Extended. Purple flowers (P) are dominant to white flowers (p). Explain how a test cross could show whether a purple-flowered plant is PP or Pp.

  • Cross the purple plant with a white-flowered plant, which must be homozygous recessive (pp). ✓
  • The pp plant only gives p, so the offspring phenotypes show the allele received from the purple plant. ✓
  • If the purple plant is PP, all the offspring are purple (Pp). ✓
  • If it is Pp, about half the offspring are white (pp): a 1 purple : 1 white ratio. Use a large number of offspring. ✓
06
Data
[3 marks]

Two pure-breeding pea plants, one with green pods and one with yellow pods, were crossed. All the F1 plants had green pods. Two F1 plants were then crossed, giving 580 plants with green pods and 202 with yellow pods. (a) State which allele is dominant. (b) Calculate the ratio green : yellow to one decimal place. (c) State the genotype of the F1 plants, using G and g.

  • (a) Green, because all the F1 had green pods even though they carried both alleles. ✓
  • (b) 580 ÷ 202 = 2.9, so about 2.9 : 1 (close to 3 : 1). ✓
  • (c) Gg (heterozygous). ✓

Mark this once you have attempted all six and checked your working. It records a Practiced badge on the topic and adds a one-time bonus. Revealing the solutions alone does not count.