Cambridge IGCSE · Topic 18.1
IGCSE Biology 0610 / Topic 18 / IGCSE

No two alike.

Line up any class and no two people are the same height, yet every one of them belongs to exactly one blood group. Variation comes in two kinds, continuous and discontinuous, and they have different causes. New alleles, the raw material of all variation, come from mutation.

The key idea

Variation is the differences between individuals of the same species. Continuous variation gives a range of phenotypes between two extremes (body length, body mass) and is caused by both genes and the environment. Discontinuous variation gives a limited number of phenotypes with no intermediates (ABO blood groups, pea seed shape and colour) and is usually caused by genes only. Mutation is genetic change and is the way new alleles are formed.

Continuous: height Discontinuous: blood group height / cm (touching bars: any value) genes + environment A B AB O separate bars: no intermediates genes only
Fig. 1: continuous variation gives a histogram with a bell-shaped spread; discontinuous variation gives separate bars with nothing in between
Section 01

Continuous variation.

In the sim a class of 40 people stands on the floor. Press Line up by height and they sort from shortest to tallest. Every height between the shortest and the tallest is possible, and the histogram builds a bell shape: most people near the middle, few at the extremes.

Examiner trap

Continuous variation is not caused by the environment alone. Set the diet slider to zero in the sim: the heights still vary, because the people have different genes.

Section 02

Discontinuous variation.

Switch between pea seed shape, pea seed colour and ABO blood group, then press Sort them. Every seed or person drops into one of a few clear groups. There is no slightly wrinkled pea and no blood group half way between A and B.

ContinuousDiscontinuous
Phenotypesa range between two extremesa limited number, no intermediates
Examplesbody length, body massABO blood group, pea seed shape (round or wrinkled), pea seed colour (yellow or green)
Caused bygenes and the environmentusually genes only
Graphhistogram, touching barsbar chart, separate bars
Examiner trap

A feature measured in numbers is not automatically continuous. Shoe size is recorded in whole sizes, but foot length is really continuous. Ask whether intermediate values exist in nature.

Section 03

Mutation makes new alleles.

The mutation tab shows one gene as a row of 30 base pairs. Pick a mutagen and press Expose for 10 years. Each base that changes flashes, and the readout counts the bases changed. Compare no mutagen, ionising radiation and a chemical such as tar.

Examiner trap

Mutagens do not aim at particular genes. They increase the rate of mutation, but which base changes is random.

Stage 1 · Learn

Check what the sim just showed you

Four quick checks. Each correct answer earns XP and records this skill on your profile.

Quick check+10 XP

In the continuous tab, what happens when the class is lined up by height?

Quick check+10 XP

You set the diet (environment) slider to zero. Why do the heights still vary?

Quick check+10 XP

After sorting pea seeds by shape, how many groups are there?

Quick check+10 XP

In the mutation tab, which choice changes the fewest bases over 10 years?

Stage 2 · Exam

Exam-style questions

Unlocks once the four checks above are done. Worth more XP, written to IGCSE Paper 2 and Paper 4 standard.

Finish the four checks above to unlock the exam questions
Exam style+20 XP

Which feature shows discontinuous variation?

Exam style+20 XP

Identical twins brought up apart differ in body mass but have the same blood group. This shows that:

Exam style+20 XP

Extended: which of these is NOT a source of genetic variation in a population?

Exam style+20 XP

Extended: a gene mutation is best described as:

Skill unlocked

Variation, mastered.

This skill is now recorded on your profile. Keep the chain going.

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Go deeper · practice
Six original Cambridge-style questions
Continuous and discontinuous variation with examples, causes and graphs, mutation and mutagens, and (Extended) gene mutation and sources of genetic variation.