Seven 3D simulations covering Topic 10 Diseases and immunity and Topic 15 Drugs. Watch diseases spread and be controlled, see the body defend itself, and explore antibodies, vaccination, cholera and antibiotic resistance. Tabs marked Extended cover the Supplement.
A pathogen is a disease-causing organism. In a transmissible disease it passes from one host to another, directly (touch, blood, body fluids) or indirectly (contaminated surfaces, food, water, animals and air). Switch the controls on and off and watch the outbreak.
The body keeps most pathogens out, and destroys those that get in. Pick a defence to see it at work.
Every pathogen has its own antigens, molecules on its surface with a specific shape. Lymphocytes make antibodies, proteins with a shape complementary to one antigen. Choose which antibody to make and see which pathogens it binds to.
Active immunity is gained by making your own antibodies, after an infection or after a vaccination, and it leaves memory cells. Passive immunity is borrowed antibodies, from the mother across the placenta or in breast milk: it works at once but fades, and leaves no memory cells. Try different histories.
When enough people are vaccinated, a pathogen cannot find enough people to infect, so the outbreak dies out and even unvaccinated people are protected. Set the vaccination rate and start an outbreak in the middle.
Cholera is caused by a bacterium spread in water contaminated with faeces. In the small intestine the bacteria release a toxin. Watch what the toxin does to the cells lining the gut, and why the patient becomes dangerously dehydrated.
A drug is any substance taken into the body that changes the chemical reactions in it. Antibiotics are drugs that kill bacteria, or stop them growing; they have no effect on viruses. Some bacteria are resistant. Treat the infection and see what happens to them.
Seven interactive 3D simulations for Cambridge IGCSE Biology 0610 topics 10 Diseases and immunity and 15 Drugs: an outbreak spreading through a town by direct contact, surfaces, water, food and flies with switchable controls, the body's defences, antigens and complementary antibodies, vaccination, memory cells and passive immunity, herd immunity, how the cholera toxin causes dehydration, and antibiotics with resistant bacteria and viruses.
Seven 3D simulations covering Topic 10 Diseases and immunity and Topic 15 Drugs. Watch diseases spread and be controlled, see the body defend itself, and explore antibodies, vaccination, cholera and antibiotic resistance. Tabs marked Extended cover the Supplement.
Diseases, immunity and drugs is a free, browser-based simulation for Cambridge IGCSE Biology 0610 (topic 10 Diseases and immunity; topic 15 Drugs). The course is assessed in Paper 1/2 (Multiple choice), Paper 3/4 (Theory), Paper 5 (Practical Test), Paper 6 (Alternative to Practical). Syllabus for examination in 2026-2028. There are 7 tabs, each a self-contained experiment with its own controls and live readings, and nothing to install: it runs on a laptop, tablet or classroom projector.
Full syllabus map: IGCSE Biology 0610 topic 10 and IGCSE Biology 0610 topic 15.
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