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9700 AS Biology/Topic 2 Biological molecules/7 interactive simulations/drag to rotate 3D scenes

Biological molecules, made interactive

Seven simulations covering Topic 2: carbohydrates and lipids (2.2), proteins (2.3), water (2.4) and the tests for biological molecules (2.1). Rotate the 3D models with drag, zoom with the wheel or pinch, and step through every reaction one bond at a time.

1. Monosaccharides in 3D 3D · 2.2

Glucose is a hexose that closes into a six-membered ring. The only difference between α-glucose and β-glucose is which way the OH group on carbon 1 points, and that one detail decides whether a chain becomes starch or cellulose. Ribose is the pentose in RNA.

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Molecule

FORMULA
TYPE
COH

2. Condensation and hydrolysis 2D · 2.2 / 2.3

Every large biological molecule is built the same way: two units join with the loss of a water molecule, and are split apart by adding one back. Step through the three bond types the syllabus needs: glycosidic, ester and peptide.

Reaction

BOND FORMED
WATER

3. Starch, glycogen and cellulose 3D · 2.2

All three are polymers of glucose, yet one is a coiled energy store, one is a heavily branched energy store, and one is a straight structural fibre. The shape of the chain comes straight from the α or β form of the monomer and from where the bonds form.

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Polysaccharide

4. Lipids: fatty acids, triglycerides and the bilayer 3D · 2.2

A fatty acid is a hydrocarbon tail with a carboxyl head. One C=C double bond puts a kink in the tail. Swap one fatty acid for a phosphate group and the molecule has a water-loving head and water-hating tails, which is why phospholipids line up into the bilayer of every membrane.

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Structure

COPH

5. Proteins: from amino acid to haemoglobin 3D · 2.3

Twenty amino acids that differ only in their R group, joined by peptide bonds into a chain. The chain then folds in stages. Step up through the four levels of structure, then compare a globular protein with a fibrous one.

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Level

6. Water 3D · 2.4

A small, bent, polar molecule that hydrogen-bonds to its neighbours. Almost every property that makes water fit for life follows from those hydrogen bonds: it is a solvent, it resists temperature change, it is cohesive, and ice floats.

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Property

propertybecausematters for
solventpolar molecules surround ions and polar solutestransport in blood and xylem; reactions in solution
high specific heat capacityenergy goes into breaking hydrogen bondsstable temperatures inside cells and in lakes
high latent heat of vaporisationmany hydrogen bonds to break to escape as gassweating and transpiration cool effectively
cohesionmolecules pull on each othercontinuous columns in xylem; surface tension
ice is less denseopen hydrogen-bonded latticeice floats and insulates the water below

7. Virtual food tests 2D · 2.1

Choose a sample and a test, then watch the tube. Benedict's is semi-quantitative: the colour tells you roughly how much reducing sugar there is. For a non-reducing sugar such as sucrose you must hydrolyse it first. Try the mystery samples and work out what they contain.

Sample

Test

Built for AS Level Biology 9700, Topic 2 Biological molecules. Molecular models are schematic: correct connectivity and ring forms, not measured bond lengths.

About this lab: Biological molecules

Seven simulations: alpha and beta glucose and ribose in 3D, condensation and hydrolysis of glycosidic, ester and peptide bonds, starch, glycogen and cellulose, fatty acids and the phospholipid bilayer, the four levels of protein structure, hydrogen bonding in water, and a virtual food-test bench with mystery samples.

Seven simulations covering Topic 2: carbohydrates and lipids (2.2), proteins (2.3), water (2.4) and the tests for biological molecules (2.1). Rotate the 3D models with drag, zoom with the wheel or pinch, and step through every reaction one bond at a time.

Biological molecules is a free, browser-based simulation for Cambridge International AS & A Level Biology 9700 (topic 2 Biological molecules). The course is assessed in Paper 1 (Multiple choice), Paper 2 (AS structured), Paper 3 (Advanced practical), Paper 4 (A Level structured), Paper 5 (Planning, analysis, evaluation). Syllabus for examination in 2025-2027. There are 7 tabs, each a self-contained experiment with its own controls and live readings, and nothing to install: it runs on a laptop, tablet or classroom projector.

Syllabus coverage

Full syllabus map: AS Level Biology 9700 topic 2.

How to use this simulation

  1. 1. Monosaccharides in 3D. Glucose is a hexose that closes into a six-membered ring.
  2. 2. Condensation and hydrolysis. Every large biological molecule is built the same way: two units join with the loss of a water molecule, and are split...
  3. 3. Starch, glycogen and cellulose. All three are polymers of glucose, yet one is a coiled energy store, one is a heavily branched energy store, and one is...
  4. 4. Lipids: fatty acids, triglycerides and the bilayer. A fatty acid is a hydrocarbon tail with a carboxyl head.
  5. 5. Proteins: from amino acid to haemoglobin. Twenty amino acids that differ only in their R group, joined by peptide bonds into a chain.
  6. 6. Water. A small, bent, polar molecule that hydrogen-bonds to its neighbours.
  7. 7. Virtual food tests. Choose a sample and a test, then watch the tube.
  8. The buttons at the end of the tab strip give the scene the whole window (Full screen, Hide controls) and, on a dark stage, a projector-friendly palette (Light scene). Many scenes also have drag handles: drag them to change the set-up directly.

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