‹ Biology simulationsBiology · A Level 9700 · 19 Genetic technologyEight 3D simulations covering Topic 19.1 Principles of genetic technology, 19.2 Genetic technology applied to medicine and 19.3 Genetically modified organisms in agriculture. Get a gene, build a recombinant plasmid, run PCR and a gel, read a microarray, edit a genome and explore uses in medicine and farming.
A gene to be transferred can be cut from donor DNA, made from mRNA, or synthesised chemically. Compare the three methods and the enzymes they use.
Recombinant DNA is DNA made by joining DNA from different sources. Insert a gene with a promoter and a fluorescent marker gene into a plasmid, put it into bacteria and check which ones express it.
PCR copies a chosen section of DNA many times. Run the thermal cycler and watch the temperature, the strands and the number of copies.
DNA fragments are separated by length in an agarose gel. Run the gel to compare DNA from a crime scene with two suspects.
A microarray has thousands of DNA probes. Labelled cDNA from two samples shows which genes are being expressed in each.
Gene editing inserts, deletes or replaces DNA at a specific site in the genome. A guide RNA leads a nuclease to the target, which cuts both strands.
Recombinant human proteins, genetic screening and gene therapy. Pick an example.
Genetic engineering can raise the quality and productivity of food. Compare each GM organism with the non-GM version, then weigh up the issues.
Eight interactive 3D simulations for Cambridge A Level Biology 9700 topic 19 Genetic technology: obtaining genes from donor DNA, from mRNA with reverse transcriptase and by chemical synthesis, recombinant plasmids with promoters and fluorescent marker genes, PCR with Taq polymerase, gel electrophoresis and DNA profiling, microarrays and sequence databases, gene editing, recombinant proteins, genetic screening and gene therapy in medicine, and GM salmon, herbicide-resistant soybean and Bt cotton.
Eight 3D simulations covering Topic 19.1 Principles of genetic technology, 19.2 Genetic technology applied to medicine and 19.3 Genetically modified organisms in agriculture. Get a gene, build a recombinant plasmid, run PCR and a gel, read a microarray, edit a genome and explore uses in medicine and farming.
Genetic technology is a free, browser-based simulation for Cambridge International AS & A Level Biology 9700 (topic 19 Genetic technology). The course is assessed in Paper 1 (Multiple choice), Paper 2 (AS structured), Paper 3 (Advanced practical), Paper 4 (A Level structured), Paper 5 (Planning, analysis, evaluation). Syllabus for examination in 2025-2027. There are 8 tabs, each a self-contained experiment with its own controls and live readings, and nothing to install: it runs on a laptop, tablet or classroom projector.
Full syllabus map: A Level Biology 9700 topic 19.
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