‹ Biology simulationsBiology · A Level 9700 · 14 HomeostasisNine 3D simulations covering Topic 14.1 Homeostasis in mammals and 14.2 Homeostasis in plants. Follow a feedback loop, explore the kidney and nephron, filter blood, release ADH, amplify a glucagon signal, balance blood glucose, test for glucose and open and close stomata.
Homeostasis keeps the internal environment near a set point using receptors, coordination systems, effectors and negative feedback. Disturb core temperature and follow the loop.
The kidneys remove urea, made in the liver by deamination of excess amino acids, and regulate the water potential of the blood. Click the parts of the cut kidney.
Each kidney has about a million nephrons. Click the parts of a nephron and its blood vessels.
The structure of the Bowman's capsule and the proximal convoluted tubule suits their jobs. Watch which substances pass through.
Osmoreceptors in the hypothalamus detect the water potential of the blood. ADH from the posterior pituitary gland makes the collecting duct more permeable to water.
One glucagon molecule binding to a liver cell triggers a cascade that releases thousands of glucose molecules. Step through it and watch the amplification.
Negative feedback keeps blood glucose near 5 mmol dm⁻³. See what insulin does to muscle and liver cells, and what glucagon does to liver cells.
Glucose oxidase and peroxidase let us measure glucose in urine or blood. Set the glucose concentration and test it.
Guard cells open and close stomata, balancing carbon dioxide uptake against water loss. Switch between day, night and drought.
Nine interactive 3D simulations for Cambridge A Level Biology 9700 topic 14 Homeostasis: the principles of homeostasis and negative feedback, the structure of the kidney, the nephron and its blood vessels, ultrafiltration in the Bowman's capsule and selective reabsorption in the proximal convoluted tubule, osmoregulation by the hypothalamus, posterior pituitary, ADH and aquaporins, cell signalling by glucagon through G proteins, cAMP and an enzyme cascade, the actions of insulin and glucagon, glucose test strips and biosensors, and the opening and closing of stomata with abscisic acid.
Nine 3D simulations covering Topic 14.1 Homeostasis in mammals and 14.2 Homeostasis in plants. Follow a feedback loop, explore the kidney and nephron, filter blood, release ADH, amplify a glucagon signal, balance blood glucose, test for glucose and open and close stomata.
Homeostasis is a free, browser-based simulation for Cambridge International AS & A Level Biology 9700 (topic 14 Homeostasis). The course is assessed in Paper 1 (Multiple choice), Paper 2 (AS structured), Paper 3 (Advanced practical), Paper 4 (A Level structured), Paper 5 (Planning, analysis, evaluation). Syllabus for examination in 2025-2027. There are 9 tabs, each a self-contained experiment with its own controls and live readings, and nothing to install: it runs on a laptop, tablet or classroom projector.
Full syllabus map: A Level Biology 9700 topic 14.
All simulation labs · A Level Biology 9700 · TheLucidSTEM home