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9700 AS Level Biology/Topic 11 Immunity/7 interactive simulations/drag to rotate the 3D models

Immunity, made interactive

Seven 3D simulations covering Topic 11.1 The immune system and 11.2 Antibodies and vaccination. Watch a phagocyte at work, sort self from non-self, step through the primary response, compare it with the secondary response, take an antibody apart, make monoclonal antibodies and vaccinate a community.

1. Phagocytes 3D · 11.1

Neutrophils and macrophages engulf and digest pathogens: an immediate, non-specific response. Release a phagocyte near some bacteria.

drag to rotate · wheel to zoom

Phagocytosis

STAGE
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BACTERIA LEFT
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2. Self and non-self antigens 3D · 11.1

Antigens are molecules, usually proteins or glycoproteins, on cell surfaces that can trigger an immune response. Click the cells to see whose antigens they carry.

click a cell · drag to rotate · wheel to zoom

Cell

3. The primary immune response 3D · 11.1

Only the lymphocytes with receptors complementary to the antigen are selected, then they divide into clones. Step through the response.

drag to rotate · wheel to zoom

Step

STEP

4. Memory cells and the secondary response 3D · 11.1

Memory cells stay in the blood after an infection. Meet the same pathogen again and compare the two responses.

drag to rotate · wheel to zoom

Exposures

5. Antibody structure and function 3D · 11.2

An antibody is a protein made of four polypeptide chains. Click its parts, then watch how antibodies act on pathogens.

click a part · drag to rotate · wheel to zoom

View

6. Monoclonal antibodies 3D · 11.2

The hybridoma method makes large amounts of one type of antibody. Step through it, then see how monoclonal antibodies are used.

drag to rotate · wheel to zoom

Steps

7. Types of immunity and vaccination 3D · 11.2

Immunity can be active or passive, natural or artificial. Vaccines give active immunity; vaccinating enough people protects the whole community.

drag to rotate · wheel to zoom

Immunity

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Built for Cambridge AS & A Level Biology 9700, Topic 11. Cells and molecules are simplified and not to scale; graphs are illustrative.

About this lab: Immunity

Seven interactive 3D simulations for Cambridge AS Level Biology 9700 topic 11 Immunity: phagocytosis by neutrophils and macrophages, self and non-self antigens, the primary immune response with antigen presentation, clonal selection and expansion, T-helper, T-killer and B-lymphocytes and plasma cells, memory cells and the secondary response, antibody structure with agglutination, neutralisation and opsonisation, the hybridoma method for monoclonal antibodies in diagnosis and treatment, and active, passive, natural and artificial immunity with herd immunity from vaccination.

Seven 3D simulations covering Topic 11.1 The immune system and 11.2 Antibodies and vaccination. Watch a phagocyte at work, sort self from non-self, step through the primary response, compare it with the secondary response, take an antibody apart, make monoclonal antibodies and vaccinate a community.

Immunity is a free, browser-based simulation for Cambridge International AS & A Level Biology 9700 (topic 11 Immunity). The course is assessed in Paper 1 (Multiple choice), Paper 2 (AS structured), Paper 3 (Advanced practical), Paper 4 (A Level structured), Paper 5 (Planning, analysis, evaluation). Syllabus for examination in 2025-2027. There are 7 tabs, each a self-contained experiment with its own controls and live readings, and nothing to install: it runs on a laptop, tablet or classroom projector.

Syllabus coverage

Full syllabus map: AS Level Biology 9700 topic 11.

How to use this simulation

  1. 1. Phagocytes. Neutrophils and macrophages engulf and digest pathogens: an immediate, non-specific response.
  2. 2. Self and non-self antigens. Antigens are molecules, usually proteins or glycoproteins, on cell surfaces that can trigger an immune response.
  3. 3. The primary immune response. Only the lymphocytes with receptors complementary to the antigen are selected, then they divide into clones.
  4. 4. Memory cells and the secondary response. Memory cells stay in the blood after an infection.
  5. 5. Antibody structure and function. An antibody is a protein made of four polypeptide chains.
  6. 6. Monoclonal antibodies. The hybridoma method makes large amounts of one type of antibody.
  7. 7. Types of immunity and vaccination. Immunity can be active or passive, natural or artificial.
  8. The buttons at the end of the tab strip give the scene the whole window (Full screen, Hide controls) and, on a dark stage, a projector-friendly palette (Light scene). Many scenes also have drag handles: drag them to change the set-up directly.

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