Cambridge IGCSE · Topic 11.1
IGCSE Biology 0610 / Topic 11 / IGCSE

Down the airways to 700 million air sacs.

Every breath travels from the larynx down the trachea, bronchi and bronchioles to the alveoli, where oxygen passes into the blood and carbon dioxide passes out. This lesson names every part, explains why the alveoli are such a good gas exchange surface and (Extended) shows how cartilage, mucus and cilia keep the airways open and clean.

The key idea

Air passes through the larynx, trachea, bronchi and bronchioles to the alveoli, tiny air sacs surrounded by capillaries. Gas exchange surfaces in humans have four features: a large surface area, a thin surface, a good blood supply and good ventilation with air. Together they keep oxygen diffusing into the blood and carbon dioxide diffusing out as fast as possible.

larynx trachea bronchus alveoli ribs diaphragm lung one alveolus air capillary oxygen into blood carbon dioxide to air
Fig. 1: the breathing system inside the thorax, and one alveolus with its capillary where oxygen and carbon dioxide are exchanged by diffusion
Section 01

From the larynx to the alveoli.

Rotate the 3D model and click each part. Air enters through the nose or mouth, passes the larynx (voice box) and goes down the trachea. The trachea divides into two bronchi, one to each lung, and these branch again and again into bronchioles that end in clusters of alveoli.

PartWhat it is
larynxthe voice box at the top of the trachea
tracheathe windpipe, carrying air from the larynx to the bronchi
bronchithe two branches of the trachea, one to each lung
bronchiolessmaller and smaller tubes branching from the bronchi
alveolitiny air sacs at the ends of the bronchioles, where gas exchange happens (about 700 million)
capillariesa dense network around every alveolus, bringing blood very close to the air
lungsthe two spongy organs of gas exchange, inside the thorax
ribsprotect the lungs and change the volume of the thorax when they move
intercostal musclesmuscles between the ribs
diaphragma sheet of muscle below the lungs that separates the thorax from the abdomen
Examiner trap

The order matters: trachea, then bronchi, then bronchioles, then alveoli. A common slip is to put bronchioles before bronchi. The singular of bronchi is bronchus, and of alveoli is alveolus.

Section 02

Four features of a gas exchange surface.

Oxygen diffuses from the air in an alveolus into the blood in the capillary, and carbon dioxide diffuses the other way. All four features start switched on. Switch one off at a time and watch the oxygen rate fall from 10 per second.

FeatureHow the lungs provide itWhy it speeds up diffusion
large surface areamillions of tiny alveoli instead of one big sacmore gas can cross at the same time
thin surfacealveolus wall and capillary wall are each one cell thickshort diffusion distance
good blood supplydense capillary network with blood always flowingoxygen is carried away and carbon dioxide brought, keeping the concentration gradients steep
good ventilation with airbreathing replaces the air in the alveolikeeps oxygen high and carbon dioxide low in the alveoli, keeping the gradients steep
Examiner trap

"Thin" refers to the surface (one cell thick), not to the lungs being thin. And a good blood supply does not push oxygen in: it carries oxygen away so the concentration gradient stays steep.

Stage 1 · Learn

Check what the sim just showed you

Four quick checks. Each correct answer earns XP and records this skill on your profile.

Quick check+10 XP

In the breathing system model, which part carries air from the larynx to the bronchi?

Quick check+10 XP

About how many alveoli does the sim say there are in the lungs?

Quick check+10 XP

In the alveoli tab, switching off which single feature lowers the oxygen rate the most?

Quick check+10 XP

Why does the oxygen rate fall when the blood supply is turned off in the sim?

Section 03

Keeping the airways clean.

Extended. The air we breathe carries dust, pollen, bacteria and viruses. In the breathing system tab, set the View to "lining of the trachea (Extended)" to see how the lining of the airways traps and removes them before they reach the alveoli.

Examiner trap

Cilia do not trap anything: the mucus traps, the cilia move the mucus. Goblet cells make mucus; they are not ciliated. Keep the three jobs separate.

Stage 2 · Exam

Exam-style questions

Unlocks once the four checks above are done. Worth more XP, written to IGCSE Paper 2 and Paper 4 standard.

Finish the four checks above to unlock the exam questions
Exam style+20 XP

Which list shows the correct order in which air passes through the breathing system?

Exam style+20 XP

Which feature of the alveoli gives a short diffusion distance?

Exam style+20 XP

Extended: what is the function of the cartilage in the wall of the trachea?

Exam style+20 XP

Extended: how do ciliated cells protect the breathing system?

Skill unlocked

The breathing system, mastered.

This skill is now recorded on your profile. Keep the chain going.

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Go deeper · practice
Six original Cambridge-style questions
Naming the parts of the breathing system, the four features of gas exchange surfaces and (Extended) cartilage, intercostal muscles, goblet cells, mucus and cilia.