Cambridge IGCSE · Topic 16.2
IGCSE Biology 0610 / Topic 16 / IGCSE

Two gametes, one zygote.

Most animals and flowering plants reproduce sexually. Two parents each make gametes, and when the nuclei of two gametes fuse the new cell, a zygote, has a mix of genes from both. That is why brothers and sisters are never exactly alike. Haploid and diploid nuclei, and the trade-offs against asexual reproduction, are Extended content.

The key idea

Sexual reproduction is a process involving the fusion of the nuclei of two gametes to form a zygote and the production of offspring that are genetically different from each other. Fertilisation is the fusion of the nuclei of gametes. Extended: the nuclei of gametes are haploid (one set of chromosomes) and the nucleus of a zygote is diploid (two sets).

male gamete female gamete haploid (n) haploid (n) fertilisation zygote diploid (2n) varied offspring
Fig. 1: two haploid gamete nuclei fuse at fertilisation to give a diploid zygote
Section 01

Gametes and fertilisation.

In the gametes tab the sperm and egg cell are drawn at the same scale. Press Release sperm. Many sperm swim to the egg, but only the first to arrive gets in, and its nucleus fuses with the egg nucleus.

Examiner trap

Fertilisation is the fusion of the nuclei, not just the sperm touching or entering the egg. Write "the nucleus of the sperm fuses with the nucleus of the egg".

Stage 1 · Learn

Check what the sim just showed you

Four quick checks. Each correct answer earns XP and records this skill on your profile.

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In the gametes tab, what happens to the jelly coat once the first sperm enters the egg?

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Which event in the sim is fertilisation?

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How many sperm fertilise the egg cell in the sim?

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What is the cell formed at fertilisation called?

Section 02

Haploid and diploid.

Extended. Body cells contain two sets of chromosomes, one set from each parent. If gametes had two sets too, the number would double every generation. So gametes carry only one set.

CellNucleusHuman example
Gamete (sperm, egg cell)haploid: one set of chromosomes23 chromosomes
Zygote and body cellsdiploid: two sets of chromosomes46 chromosomes (23 pairs)
Section 03

Sexual versus asexual.

Extended. Variation is the big advantage of sexual reproduction, but it comes at a cost in time and effort. Compare the two methods for a species in the wild and for a farmer growing crops.

Advantages of sexual reproductionDisadvantages
Population in the wildvariation, so some individuals may survive a new disease or a change in the environment; the species can adapt (natural selection); seeds can spread offspring far from the parentslower; needs two parents (or a pollinator or the wind), so a lone individual cannot reproduce; energy spent finding a mate or making flowers and nectar
Crop productionnew varieties can be bred with better yield or disease resistance; seeds are easy to store and transportoffspring vary, so good features of a parent may be lost; slower to reach harvest; growth from seed is less predictable
Examiner trap

Variation is an advantage for the population, not a guarantee for each individual. Write that some individuals are likely to survive a change, so the species is less likely to die out.

Stage 2 · Exam

Exam-style questions

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Which statement about sexual reproduction is correct?

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Extended: a cat has 38 chromosomes in its body cells. How many are in the nucleus of a cat egg cell?

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Extended: why is it important that gamete nuclei are haploid?

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Extended: which is a disadvantage of sexual reproduction for a population in the wild?

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Sexual reproduction, mastered.

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Six original Cambridge-style questions
Gametes, fertilisation and zygotes, genetically different offspring, and (Extended) haploid and diploid nuclei and the advantages and disadvantages of sexual reproduction.